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{"id":16488,"date":"2020-03-12T18:55:52","date_gmt":"2020-03-12T18:55:52","guid":{"rendered":"http:\/\/107.23.69.64\/?p=16488"},"modified":"2020-03-12T18:55:52","modified_gmt":"2020-03-12T18:55:52","slug":"sickle-cell-anemia","status":"publish","type":"post","link":"https:\/\/shakshope.com\/sickle-cell-anemia\/","title":{"rendered":"Sickle Cell Anemia"},"content":{"rendered":"[ad_1]<\/p>\n
We will discuss what causes sickle cell anemia, what the symptoms are, what is done to treat this disease, and tests available.<\/p>\n
CAUSES<\/b><\/p>\n\n- It’s inherited. The inherited gene causes the body to make abnormal hemoglobin “S.” Normal hgb is “A.” <\/li>\n
- One inherited gene will cause Sickle Cell Trait which can be passed on to the next generation. Two genes will cause Sickle Cell Disease.<\/li>\n
- The disease is present at birth, but babies usually don’t show symptoms until about four months old.<\/li>\n
- The abnormal hemoglobin (hgb) causes the red blood cells to be crescent shaped, like a sickle. Normal red cells are doughnut shaped. These sickle shaped red blood cells clump together and get caught in blood vessels.<\/li>\n
- The abnormal hemoglobin (hgb) causes anemia. Hemoglobin is made of protein and iron. Hgb “S” does not have as much iron as normal hgb.<\/li>\n<\/ul>\n
SYMPTOMS<\/b><\/p>\n\n- The most common symptom is sudden pain. This is due to the abnormal red cells getting caught in the blood vessels in the limbs and organs.<\/li>\n
- Fatigue. This is due to the anemia.<\/li>\n
- Chest pain. This is caused by the cells getting trapped in the lungs, or an infection.<\/li>\n
- Dizziness<\/li>\n
- Headache<\/li>\n
- Cold hands and feet<\/li>\n
- Infections. These are due to the spleen being damaged. Your spleen helps to fight infections.<\/li>\n<\/ul>\n
TESTS<\/b><\/p>\n\n- A red cell analysis(CBC or ABC), including studying the cells under a microscope, will show the shape of the cells.<\/li>\n
- The “Sickle Cell Test” determines if abnormal hgb is present in the blood. A deoxygenating agent is added to the blood. A technologist examines the sample under the microscope to look for sickled cells. This shows if the patient has either the trait or the disease.<\/li>\n
- Hemoglobin electrophoresis determines the type of hgb by passing an electric charge through a solution of the patient’s blood. Different hgb’s travel different distances.<\/li>\n<\/ul>\n
TREATMENT<\/b><\/p>\n\n- Pain management<\/li>\n
- IV fluids. It’s important for the patient to drink lots of fluids to help prevent a sickle cell crisis.<\/li>\n
- Antibiotics for infection<\/li>\n
- Vaccination against pneumonia<\/li>\n
- Blood transfusion<\/li>\n
- Medication to prevent a painful crisis. There are possible serious side effects to the medication, however.<\/li>\n
- Possible bone marrow transplant<\/li>\n<\/ul>\n
Carriers of the trait may choose to consult a genetic counselor. Scientists are currently researching gene therapy. They’re also searching for new medicines, with hope that their research will provide better treatment for this disease.<\/p>\n
[ad_2]
\n
Source<\/a> by Beth Blake<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"[ad_1] We will discuss what causes sickle cell anemia, what the symptoms are, what is done to treat this disease, and tests available. CAUSES It’s inherited. The inherited gene causes the body to make abnormal hemoglobin “S.” Normal hgb is “A.” One inherited gene will cause Sickle Cell Trait which can be passed on to…<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[17],"tags":[36],"_links":{"self":[{"href":"https:\/\/shakshope.com\/wp-json\/wp\/v2\/posts\/16488"}],"collection":[{"href":"https:\/\/shakshope.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/shakshope.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/shakshope.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/shakshope.com\/wp-json\/wp\/v2\/comments?post=16488"}],"version-history":[{"count":0,"href":"https:\/\/shakshope.com\/wp-json\/wp\/v2\/posts\/16488\/revisions"}],"wp:attachment":[{"href":"https:\/\/shakshope.com\/wp-json\/wp\/v2\/media?parent=16488"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/shakshope.com\/wp-json\/wp\/v2\/categories?post=16488"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/shakshope.com\/wp-json\/wp\/v2\/tags?post=16488"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}