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	<title>sickle cell anemia &#8211; Shaks Hope</title>
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	<description>Fighting the Sickle Cell disease one day at a time...</description>
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		<title>Sickle Cell Anemia</title>
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		<pubDate>Thu, 12 Mar 2020 18:55:52 +0000</pubDate>
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					<description><![CDATA[[ad_1] We will discuss what causes sickle cell anemia, what the symptoms are, what is done to treat this disease, and tests available. CAUSES It&#8217;s inherited. The inherited gene causes the body to make abnormal hemoglobin &#8220;S.&#8221; Normal hgb is &#8220;A.&#8221; One inherited gene will cause Sickle Cell Trait which can be passed on to...]]></description>
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<p>We will discuss what causes sickle cell anemia, what the symptoms are, what is done to treat this disease, and tests available.</p>
<p><b>CAUSES</b></p>
<ul>
<li>It&#8217;s inherited. The inherited gene causes the body to make abnormal hemoglobin &#8220;S.&#8221; Normal hgb is &#8220;A.&#8221; </li>
<li>One inherited gene will cause Sickle Cell Trait which can be passed on to the next generation. Two genes will cause Sickle Cell Disease.</li>
<li>The disease is present at birth, but babies usually don&#8217;t show symptoms until about four months old.</li>
<li>The abnormal hemoglobin (hgb) causes the red blood cells to be crescent shaped, like a sickle. Normal red cells are doughnut shaped. These sickle shaped red blood cells clump together and get caught in blood vessels.</li>
<li>The abnormal hemoglobin (hgb) causes anemia. Hemoglobin is made of protein and iron. Hgb &#8220;S&#8221; does not have as much iron as normal hgb.</li>
</ul>
<p><b>SYMPTOMS</b></p>
<ul>
<li>The most common symptom is sudden pain. This is due to the abnormal red cells getting caught in the blood vessels in the limbs and organs.</li>
<li>Fatigue. This is due to the anemia.</li>
<li>Chest pain. This is caused by the cells getting trapped in the lungs, or an infection.</li>
<li>Dizziness</li>
<li>Headache</li>
<li>Cold hands and feet</li>
<li>Infections. These are due to the spleen being damaged. Your spleen helps to fight infections.</li>
</ul>
<p><b>TESTS</b></p>
<ul>
<li>A red cell analysis(CBC or ABC), including studying the cells under a microscope, will show the shape of the cells.</li>
<li>The &#8220;Sickle Cell Test&#8221; determines if abnormal hgb is present in the blood. A deoxygenating agent is added to the blood. A technologist examines the sample under the microscope to look for sickled cells. This shows if the patient has either the trait or the disease.</li>
<li>Hemoglobin electrophoresis determines the type of hgb by passing an electric charge through a solution of the patient&#8217;s blood. Different hgb&#8217;s travel different distances.</li>
</ul>
<p><b>TREATMENT</b></p>
<ul>
<li>Pain management</li>
<li>IV fluids. It&#8217;s important for the patient to drink lots of fluids to help prevent a sickle cell crisis.</li>
<li>Antibiotics for infection</li>
<li>Vaccination against pneumonia</li>
<li>Blood transfusion</li>
<li>Medication to prevent a painful crisis. There are possible serious side effects to the medication, however.</li>
<li>Possible bone marrow transplant</li>
</ul>
<p>Carriers of the trait may choose to consult a genetic counselor. Scientists are currently researching gene therapy. They&#8217;re also searching for new medicines, with hope that their research will provide better treatment for this disease.</p>
<p>[ad_2]<br />
<br /><a href="https://ezinearticles.com/?Sickle-Cell-Anemia&#038;id=2148686">Source</a> by <a href="http://ezinearticles.com/expert/Beth_Blake/280696">Beth Blake</a></p>
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